Andrzej Jerzmanowski

Company
Polish Academy of Sciences

Address
Laboratory of Plant Molecular Biology, Warsaw University and Institute of Biochemistry and Biophysics
Pawińskiego 5A
02-106 Warsaw

Telephone
+48 22-5925704

E-mail
andyj@ibb.waw.pl

1. Summary of work to be allocated into a specific WG

This partner will perform analyses of changes in chromatin occurring in response to abiotic stresses, including modifications of DNA and histones, ATP-dependent remodeling of nucleosomes and patterns of histone variants, to find links between signalling pathways and chromatin-mediated regulation of specific genes. The work is mostly integrated into WG2.

2. Links with other WG and/or Subgroups  

The work is also linked with WG1.7, WG2.1, WG2.4  in order to reveal novel associations of chromatin mediated mechanisms with stress signaling and control of metabolic pathways.

3. Specific activities to be integrated into WG and/or Subgroups

WG2: The work will be concentrated on chromatin responses to stress signalling

WG1.7: Development of systems biology approaches to reveal interaction networks involving chromatin components.

WG2.1. For identification of chromatin components specifically involved in ABA-mediated signalling.

WG2.4: This will concentrate on chromatin responses during cold-stress signalling.

4. Qualification for the role and current grants

Andrzej Jerzmanowski is Full Professor at the Faculty of Biology Warsaw University and the Institute of Biochemistry and Biophysics Polish Academy of Sciences in Warsaw.  He has over 20 years of experience in studying the role of chromatin, in particular the ATP-dependent chromatin remodeling and linker (H1) histones in plants. His work is currently financed by two national grants from the Ministry of Science and Higher Education.

5. Technical expertise and facilities

This partner will provide the experience in different methods of chromatin analysis like histone quantification, chromatin immunoprecipitation, assaying of histone and DNA modifications, in vitro remodeling assays etc.  His laboratory has also experience in mass spectrometric analysis of histones and other nuclear proteins, protein overexpression, and in planta visualization of fluorescent labeled proteins. The laboratory is fully equipped to carry on the work  and has access to state-of-the art facilities in proteomics and transcriptomics at the Institute of Biochemistry and Biophysics of the Polish Academy of Sciences.