Instituto de Biología Molecular y Celular de Plantas (IBMCP, CSIC-UPV)
Campus de la UPV, Edificio CPI 8E
Avd de los Naranjos
1. Summary of work to be allocated into a specific WG
This partner will perform genetic analysis to identify/generate ABA-hypersensitive mutants in Arabidopsis. Protein phosphatases type-2C (PP2Cs), which are key negative regulators of ABA signaling pathway, will be characterized with respect to regulation of SnRK2s and SWI/SNF chromatin remodeling complexes. The work is integrated into WG1 and 2.
2. Links with other WG and/or Subgroups
The work is covered by WG2.5 and is linked with WG1.5 and WG2.3.
3. Specific activities to be integrated into WG and/or Subgroups
WG1.5: Specific studies of SnRK1/2 regulatory interactions. Interactions with PP2Cs.
WG2.3: Study of involvement of subunits of plant SWI/SNF chromatin remodeling complexes during stress responses. Interactions with PP2Cs.
WG2.5: Identification of ABA-hypersensitive mutants using forward and reverse genetics.
4. Qualification for the role and current grants
Pedro L. Rodriguez is staff scientist of the Spanish Research Council. He has 10 years of experience in the field of ABA biosynthesis and signaling. Our group has isolated and characterized alleles of the loci involved in the biosynthetic pathway, and currently mutants of the whole ABA biosynthetic pathway are available in our laboratory. In the field of ABA signaling, we have characterized negative regulators of the hormone signaling pathway, particularly PP2Cs. Strong ABA-hypersensitive mutants have been generated by combined inactivation of PP2Cs, as well as ABA-insensitive lines by overexpression of HAB1. The work is currently financed by a national grant (BIO2005-01760).
5. Technical expertise and facilities
This partner has a wide experience in Arabidopsis genetics, particularly applied to the field of ABA biosynthesis and signaling. Standard laboratory facilities for plant molecular biology studies are available. The IBMCP institute has facilities for transcriptomics.